Central Alerting System
Central Alerting System Homepage


The Central Alerting System (CAS) is a web-based cascading system for issuing patient safety alerts, important public health messages and other safety critical information and guidance to the NHS and others, including independent providers of health and social care.

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When we provide services, we want to make them easy, useful and reliable. Where services are delivered on the internet, this sometimes involves placing small amounts of information on your device, for example, computer or mobile phone. These include small files known as cookies. They cannot be used to identify you personally. More Information can be found in the Help section under Cookie usage.

Our updated privacy notice can be found here.


25/05/2022: We have updated the alert deadline on NatPSA/2022/002/MHRA to 12/07/2022.

Extended deadlines: given the current situation the below alert deadlines have been extended:This afternoon we have issued a new alert under reference NatPSA/2022/001/MHRA; this was issued in error. We are arranging to remove this alert from the website, there is no need to record any response. We have updated alert NatPSA/2022/002/MHRA. A further email will be sent to recipients this afternoon - 03/05/2022

EFA 2020/001 - extended to 12 February 2021
EFA/2019/005 - extended to 30 April 20 ...
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Contact our helpdesk

Email: safetyalerts@mhra.gov.uk

Medicines and Healthcare products Regulatory Agency