Central Alerting System Homepage


The Central Alerting System (CAS) is a web-based cascading system for issuing patient safety alerts, important public health messages and other safety critical information and guidance to the NHS and others, including independent providers of health and social care.

Alerts available on the CAS website include NHS Improvement Patient Safety Alerts (PSA) and Estates Alerts, MHRA Dear Doctor letters, Medical Device Alerts (MDA) and Drug Alerts, Chief Medical Officer (CMO) Alerts, and Department of Health & Social Care Supply Disruption alerts.

Useful links:

The Medicines and Healthcare products Regulatory Agency: http://gov.uk/mhra

NHS Improvement: https://improvement.nhs.uk/resources/patient-safety-alerts/

National Reporting & Learning System: email: patientsafetyhelpdesk@nrls.nhs.uk

The Chief Medical Officer (for England): https://www.gov.uk/government/people/sally-davies

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MDA/2019/019 - Please note that the Field Safety Notice (FSN) for this alert has been updated with some changes though the actions for users are still the same. You can access the updated FSN through the link in the alert - added 23/05/2019

MDA/2019/016 - CAS Liaison Officers please close MDA/2019/015 as action to not required - superseded by alert MDA/2019/016.  MDA/2019/016 is an update on MDA/2019/015 and therefore you should follow the actions listed in the most recent MDA.  In terms of the difference between the two alerts we have added an additional action point ...
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Contact our helpdesk

Email: safetyalerts@mhra.gov.uk

Medicines and Healthcare products Regulatory Agency