Central Alerting System Homepage


The Central Alerting System (CAS) is a web-based cascading system for issuing patient safety alerts, important public health messages and other safety critical information and guidance to the NHS and others, including independent providers of health and social care.

Alerts available on the CAS website include National Patient Safety Alerts (from MHRA, NHS England and NHS Improvement and the UK Health Security Agency (UKHSA)), NHS England and NHS Improvement Estates Alerts, Chief Medical Officer (CMO) Alerts, and Department of Health & Social Care Supply Disruption alerts.

Useful links:

National Patient Safety Alerts: https://www.england.nhs.uk/patient-safety/patient-safety-alerts/

The Medicines and Healthcare products Regulatory Agency: http://gov.uk/mhra

NHS England and NHS Improvement: https://improvement.nhs.uk/resources/patient-safety-alerts/

When we provide services, we want to make them easy, useful and reliable. Where services are delivered on the internet, this sometimes involves placing small amounts of information on your device, for example, computer or mobile phone. These include small files known as cookies. They cannot be used to identify you personally. More Information can be found in the Help section under Cookie usage.

Our updated privacy notice can be found here.


Extended deadlines: given the current situation the below alert deadlines have been extended:

EFA 2020/001 - extended to 12 February 2021
EFA/2019/005 - extended to 30 April 2021

Tell us what you think of the new National Patient Safety Alert by sharing your views here: https://engage.improvement.nhs.uk/insight/national-patient-safety-credentialing-committee-su

CAS Liaison Officers - we understand that some of you use an email auto forward to share all alerts you receive with colleagues. Each alert suggests who it will be relevant to, some require sen ...
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Contact our helpdesk

Email: safetyalerts@mhra.gov.uk

Medicines and Healthcare products Regulatory Agency