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Originator: CAS - Helpdesk - Team

From: Ben Scott

Issue date: 02-Nov-2026 16:34:38

This alert has been issued to:
  • Care Trusts
  • Mental Health Trusts
  • Other contacts
  • Specialists Trusts
  • Independent Healthcare Providers (registered with CAS)
  • Clinical Commissioning Groups
  • NHS Regional Offices
  • Learning Disabilities Trusts
  • Mental Health & Social Care Trusts
  • Ambulance Trusts
  • Social Care Providers (registered with CAS)
  • Special Health Authorities
  • Mental Health & Learning Disabilities Trusts
  • Territorial CMOs in Northern Ireland, Scotland & Wales
  • Regional Directors of Public Health
  • Director of Public Health
  • Acute Trusts
  • Community Trusts
  • GP - Locum
  • NHS 111 and Out of hours providers
  • Dispensing GP Practices
  • GP Practices
  • Integrated Care Boards
  • Out of hours contacts
  • Community Pharmacy
  • Primary Care Networks
  • GP Practices 1

Action category: Non urgent (cascade within 48 hours)

Title: Event: Influenza activity in England: implications for clinical practice and laboratory referral

Broadcast content:

·       Influenza is now circulating in the community with earlier than usual onset of activity in the 2026 to 2027 season. Data show co-circulation of a drifted strain of Influenza A(H1N1)pdm09 (within subclade D.3.1.1) and Influenza A(H3N2) (subclade K), with dominance of H1N1 in the most recent weeks.

  •        All eligible groups, including healthcare workers, should be encouraged to get vaccinated with the 2026 to 2027 seasonal influenza vaccine as soon as possible.
  •        Prompt antiviral post exposure prophylaxis and treatment for seasonal influenza should be offered to eligible groups (ideally within 48 hours of exposure or symptom onset).
  •        Antivirals guidance for treatment and prophylaxis of seasonal influenza has been updated – health professionals should familiarise themselves with the key updates, including updates to treatment recommendations for critically ill adult patients in whom treatment cannot be initiated promptly as well as updates to dosing for individuals with kidney disease.
  •        Following relevant exposure, antiviral prophylaxis should be offered to eligible people in at-risk groups irrespective of vaccination status in light of the evidence of a drifted strain.

Event: Influenza activity in England: implications for clinical practice and laboratory referral



Alert reference: MHRA

Attachments:

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