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Originator: National Patient Safety Alert - DHSC

Issue date: 01-Oct-2026 13:24:49

This alert has been issued to:
  • Care Trusts
  • Mental Health Trusts
  • Specialists Trusts
  • Learning Disabilities Trusts
  • Mental Health & Social Care Trusts
  • Ambulance Trusts
  • Mental Health & Learning Disabilities Trusts
  • Acute Trusts
  • Community Trusts

  • Other contacts
  • Independent Healthcare Providers (registered with CAS)
  • Clinical Commissioning Groups
  • NHS Regional Offices
  • Special Health Authorities
  • Territorial CMOs in Northern Ireland, Scotland & Wales
  • GP - Locum
  • NHS 111 and Out of hours providers
  • Dispensing GP Practices
  • GP Practices
  • Integrated Care Boards
  • Community Pharmacy
  • Primary Care Networks
  • GP Practices 1

Action category: Action

Title: Levemir® (insulin detemir) FlexPen® 100units/ml solution for injection 3ml pre-filled pens and Levemir® (insulin detemir) Penfill® 100units/ml solution for injection 3ml cartridges

Broadcast content:

This alert is to supplement previous communications issued:

Medicine Supply Notification (MSN/2025/036)    – issued on 16th June 2025;

Medicine Supply Notification (MSN/2025/036U) – issued on 14th August 2025; and

Medicine Supply Notification (MSN/2025/036U2) – issued on 15th April 2026.

Levemir® (insulin detemir) FlexPen® 100units/ml solution for injection 3ml pre-filled pens and Levemir® (insulin detemir) Penfill® 100units/ml solution for injection 3ml cartridges are being discontinued from end of December 2026 with stocks anticipated to be exhausted by this date.

 

Levemir® is a long-acting insulin analogue with a prolonged duration of effect used as a basal insulin. It is licensed for the treatment of diabetes mellitus in adults, adolescents and children aged 1 year and above. It can be used alone as the basal insulin or in combination with bolus insulin. It can also be used in combination with oral antidiabetic medicinal products and/or GLP-1 receptor agonists.

 

A range of alternative insulins from other suppliers are available. NOTE A

 

Please refer to the SPS Medicines Supply Tool entry for the discontinuation of Levemir® products for an overview of the supply situation and up to date supply stock overview of recommended insulins. The Medicines Supply Tool should be monitored regularly, as supply capabilities of alternative options remain subject to change.

This National Patient Safety Alert provides further background, clinical information and actions for providers. 


Additional information: NHS England Regions: Please cascade this alert to Community Pharmacy

Alert reference: NatPSA/2026/006/DHSC

Action underway deadline: 05-Oct-2026

Action complete deadline: 30-Nov-2026

Attachments:

Contact our helpdesk

Email: safetyalerts@mhra.gov.uk

Medicines and Healthcare products Regulatory Agency