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Originator: National Patient Safety Alert - DHSC

Issue date: 03-May-2024 09:20:09

This alert has been issued to:
  • Care Trusts
  • Mental Health Trusts
  • Specialists Trusts
  • Learning Disabilities Trusts
  • Mental Health & Social Care Trusts
  • Ambulance Trusts
  • Mental Health & Learning Disabilities Trusts
  • Acute Trusts
  • Community Trusts

  • Other contacts
  • Independent Healthcare Providers (registered with CAS)
  • Clinical Commissioning Groups
  • Special Health Authorities
  • Territorial CMOs in Northern Ireland, Scotland & Wales
  • Integrated Care Boards

Action category: Action

Title: Shortage of Erelzi (etanercept) 50mg solution for injection in pre-filled pen

Broadcast content:

Erelzi® (etanercept) 50mg solution for injection in pre-filled pen will be out of stock from early May until mid-July 2024. Homecare providers (Alcura, Healthnet and Sciensus) have sufficient stock to supply existing patients until mid/late May 2024.

The supply issues have been caused by a manufacturing failure resulting in delays in production and the implementation of global allocations. 

  • Erelzi® 50mg pre-filled syringes (PFS) remain available, however, they cannot support a full increase in demand.
  • Benepali® (etanercept) 50mg solution for injection in pre-filled pens remains available and can support a full increase in demand on an ongoing basis.
  • Enbrel® (etanercept) 50mg solution for injection in pre-filled pens remain available and can support a full increase in demand on an ongoing basis.

The SPS Medicines Supply Tool details any changes to resupply dates, updates to this communication and an up-to-date supply overview.

This National Patient Safety Alert provides further background, clinical information and actions for providers.



Additional information: This alert does not need to be distributed to primary care.

Alert reference: NatPSA/2024/005/MVA

Action underway deadline: 08-May-2024

Action complete deadline: 10-May-2024

Attachments:

Contact our helpdesk

Email: safetyalerts@mhra.gov.uk

Medicines and Healthcare products Regulatory Agency