| Originator: |
|
National Patient Safety Alert - DHSC
|
 |
|
|
- Care Trusts
- Mental Health Trusts
- Specialists Trusts
- Learning Disabilities Trusts
- Mental Health & Social Care Trusts
- Ambulance Trusts
- Mental Health & Learning Disabilities Trusts
- Acute Trusts
- Community Trusts
|
|
|
- Other contacts
- Independent Healthcare Providers (registered with CAS)
- Clinical Commissioning Groups
- NHS Regional Offices
- Social Care Providers (registered with CAS)
- Special Health Authorities
- Territorial CMOs in Northern Ireland, Scotland & Wales
- Regional Directors of Public Health
- Director of Public Health
- GP - Locum
- NHS 111 and Out of hours providers
- GP Practices
- DHSC Supply Disruption - Medicines
- Community Pharmacy
- Primary Care Networks
- GP Practices 1
|
| Title: |
|
Shortage of GLP-1 receptor agonists
|
| Broadcast content: |
|
***Please note this alert has been superseded by NatPSA/2024/001/DHSC, issued 03/01/2024***
There are very limited, intermittent supplies of all glucagon-like
peptide-1 receptor agonists (GLP-1 RAs).
Supplies are not expected to stabilise to meet full market demand until at least mid-2024.
The supply issues have been caused by an increase in demand for these products for licensed and off-label indications.
The off-label use of these agents for the management of obesity is strongly discouraged. Existing stock must be conserved for use in patients with diabetes. These shortages have serious clinical implications in the management of patients with type 2 diabetes.
This National Patient Safety Alert provides further background and clinical information and actions for providers.
*** 28 September 2023: the original alert pdf has been updated to amend the wording
under action 3. i. to refer to NICE NG28. This replaces the incorrect reference
to NICE CG28 in the original pdf. No other changes have been made.***
|
| Additional information: |
|
NHS England Regions: please cascade this National Patient Safety Alert to community pharmacy.
|
| Action underway deadline: |
|
28-Sep-2023
|
| Action complete deadline: |
|
18-Oct-2023
|