CAS-ViewAlert

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		Versions:

Originator:	National Patient Safety Alert - DHSC
Issue date:	Originally issued on 18-Jul-2023 08:46:03. This version was issued on 18-Jul-2023 08:46:03
This alert has been issued to:
	Care Trusts Mental Health Trusts Specialists Trusts Learning Disabilities Trusts Mental Health & Social Care Trusts Ambulance Trusts Mental Health & Learning Disabilities Trusts Acute Trusts Community Trusts
	Other contacts Independent Healthcare Providers (registered with CAS) Clinical Commissioning Groups NHS Regional Offices Social Care Providers (registered with CAS) Special Health Authorities Territorial CMOs in Northern Ireland, Scotland & Wales Regional Directors of Public Health Director of Public Health GP - Locum NHS 111 and Out of hours providers GP Practices DHSC Supply Disruption - Medicines Community Pharmacy Primary Care Networks GP Practices 1
Action category:	Action
Title:	Shortage of GLP-1 receptor agonists
Broadcast content:	There are very limited, intermittent supplies of all glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Supplies are not expected to stabilise to meet full market demand until at least mid-2024. The supply issues have been caused by an increase in demand for these products for licensed and off-label indications. The off-label use of these agents for the management of obesity is strongly discouraged. Existing stock must be conserved for use in patients with diabetes. These shortages have serious clinical implications in the management of patients with type 2 diabetes. This National Patient Safety Alert provides further background and clinical information and actions for providers. * 28 September 2023: the original alert pdf has been updated to amend the wording under action 3. i. to refer to NICE NG28. This replaces the incorrect reference to NICE CG28 in the original pdf. No other changes have been made.*
Additional information:	NHS England Regions: please cascade this National Patient Safety Alert to community pharmacy.
Alert reference:	NatPSA/2023/008/DHSC
Action underway deadline:	28-Sep-2023
Action complete deadline:	18-Oct-2023
Attachments:	NatPSA_2023_008_DHSC-.pdf