Originator: |
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DHSC & NHS England and Improvement: Supply disruption alert
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- Care Trusts
- Mental Health Trusts
- Specialists Trusts
- NHS Regional Offices
- Learning Disabilities Trusts
- Mental Health & Social Care Trusts
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- Acute Trusts
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- MHRA (Medicines) Drug Alerts (Various Recipients)
- Other contacts
- Independent Healthcare Providers (registered with CAS)
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- NHS 111 and Out of hours providers
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- DHSC Supply Disruption - Medicines
- Community Pharmacy
- Primary Care Networks
- GP Practices 1
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Title: |
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Diazepam RecTubes 2.5mg Rectal Solution - Supply Disruption
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Broadcast content: |
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- Diazepam RecTubes® 2.5mg have been discontinued in the UK and remaining supplies are expected to be exhausted by March 2022.
- Diazepam RecTubes® are licensed in acute severe anxiety and agitation, epileptic and febrile convulsions, tetanus and as a sedative in minor surgical and dental procedures or in other circumstances where rapid effect is required and where intravenous injection is not appropriate.
- Diazepam RecTubes® 2.5mg are mainly used in the management of status epilepticus and convulsions in neonates (off-label) to deliver doses of 1.25mg- 2.5mg doses and repeated if required.
- Clinicians across healthcare settings should review all patients prescribed Diazepam RecTubes® 2.5mg and relevant local guidelines/ protocols which recommend the use of Diazepam RecTubes® 2.5mg to consider alternative preparations where appropriate.
- Diazepam 5mg/ 2.5mL rectal solution remain available and can support an uplift in demand.
- Alternative parenteral and non-parenteral preparations remain available.
This alert contains further information and action for providers.
Please note that no response is required via the CAS website to this alert.
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Additional information: |
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NHS England and NHS Improvement Regional Offices: please cascade this alert to Community Pharmacy and Dental contractors.
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